This server performs in silico nano-dissection, an approach we developed to identify genes with novel cell-lineage specific expression. This method leverages high-throughput functional genomics data from tissue homogenates to accurately predict genes enriched in specific cell types.
W. Ju#, C.S. Greene#, F. Eichinger, V. Nair, J.B. Hodgin, M. Bitzer, Y. Lee, Q. Zhu, M. Kehata, M. Li, M.P. Rastaldi, C.D. Cohen, O.G. Troyanskaya*, and M. Kretzler*. Defining cell type specificity at the transcriptional level in human disease. Genome Research. 23:1862-1873. 2013. [link]